Reacción #1747852

Ecuación de reacción

4-carboxyphenylthiourea

DIC

→

Phenylthiourea

Disolventes

DMF

Condiciones de reacción

Tratamiento posterior

1. 1
   OtroAminopropylsilylated glass surfaces purified with compressed air (2.5×7.5 cm; Sigma, Silane-Prep™, S4651)
2. 2
   Otrothus obtained
3. 3
   workup.ADDITIONThe glass surfaces thus treated
4. 4
   Lavadowere then washed five times
5. 5
   Otrofor 3 minutes
6. 6
   Otroat room temperature
7. 7
   LavadoAfter washing three times for three minutes each using respectively 30 mL of DCM at room temperature
8. 8
   Otrothe glass surfaces were dried
9. 9
   Otrostored at 4° C. until further use

Procedimiento

4-carboxyphenylthiourea (Lancaster, 13047) was dissolved to 0.2M in DMF. The resultant mixture was activated by adding a half equivalent of DIC for 15 min at room temperature. Aminopropylsilylated glass surfaces purified with compressed air (2.5×7.5 cm; Sigma, Silane-Prep™, S4651) were coated with the activated solution thus obtained and incubated for three hours at room temperature. The glass surfaces thus treated were then washed five times using respectively 30 mL of DMF for 3 minutes each at room temperature. After washing three times for three minutes each using respectively 30 mL of DCM at room temperature, the glass surfaces were dried and stored at 4° C. until further use.

Fuente