Reacción #1746142

Ecuación de reacción

2,3,6-Trimethylaniline

2-chloroacetaldehyde

sodium carbonate

→

2-(2,3,6-trimethylanilino)acetaldehyde

Condiciones de reacción

Tratamiento posterior

1. 1
   Otroequipped with a mechanical stirrer
2. 2
   Temperaturathermometer and reflux condenser
3. 3
   FiltraciónAfter this time the mixture is filtered
4. 4
   workup.DISTILLATIONthe filtrate is distilled

Procedimiento

2,3,6-Trimethylaniline (0.3 mole), the dimethyl acetal of 2-chloroacetaldehyde (0.3 mole) and sodium carbonate (20 grams) are charged into a glass reaction vessel equipped with a mechanical stirrer, thermometer and reflux condenser. The reaction mixture is heated at about 150°C for a period of about 8 hours. After this time the mixture is filtered and the filtrate is distilled to yield the desired product the dimethyl acetal of 2-(2,3,6-trimethylanilino)acetaldehyde.

Fuente