Reacción #1704895
ord-5dd6bd1c300746e78a5b9a6e425d37f7
Ecuación de reacción
tetrahydrofuran
4-[3-(1-methyl-6-oxo-1,6-dihydro-pyridin-3-yl)-3-oxo-1-o-tolyl-propyl]-benzoic acid
4-[3-(1-Methyl-6-oxo-1,6-dihydro-pyridin-3-yl)-3-oxo-1-o-tolyl-propyl]-benzoic acid
sarcosine methyl ester hydrochloride
BOP reagent
→
title compound
(Methyl-{4-[3-(1-methyl-6-oxo-1,6-dihydro-pyridin-3-yl)-3-oxo-1-o-tolyl-propyl]-benzoyl}-amino)-acetic acid methyl ester
Reactantes
Reactivos
Ninguno
Condiciones de reacción
Condiciones detalladas
See reaction.notes.procedure_details.
Procedimiento
In analogy to example 207, step 2, 4-[3-(1-methyl-6-oxo-1,6-dihydro-pyridin-3-yl)-3-oxo-1-o-tolyl-propyl]-benzoic acid (example 207, step 1) was coupled with sarcosine methyl ester hydrochloride using BOP reagent in tetrahydrofuran to give the title compound as a colorless solid, MS (ESI+): m/z=461.3 [M+H]+