Reacción #1688257

Ecuación de reacción

NH3

methyl (±)-indoline-2-carboxylate

→

title compound

Rendimiento 85.0%

(±)-Indoline-2-carboxamide

Rendimiento 85.0%

Disolventes

methanol

Condiciones de reacción

Tratamiento posterior

1. 1
   Filtraciónwas filtered

Procedimiento

Gaseous NH3 was bubbled into a solution of methyl (±)-indoline-2-carboxylate (4.3 g, 24.2 mmol) in methanol (50 mL) at RT for 30 min. The reaction was stirred for 18 h, then was filtered to afford the title compound (3.35 g 85%) as a colorless solid: MS (ES) m/e 163.0 (M+H)+.

Fuente