Reacción #1687619

Ecuación de reacción

3-Cyanopyridine

methyl iodide

methyl iodide

→

title compound

Rendimiento 81.0%

3-Cyano-1-methylpyridinium Iodide

Rendimiento 81.0%

Disolventes

acetone

Condiciones de reacción

Tratamiento posterior

1. 1
   FiltraciónThe mixture was filtered
2. 2
   Lavadothe solid product was washed with acetone (100 ml)
3. 3
   OtroAfter drying

Procedimiento

3-Cyanopyridine (1) (104 g, 1 mol) and methyl iodide (150 g, 1.06 mol) in acetone (500 ml) was stirred for 5 hours at room temperature. Then more methyl iodide (20 g, 0.14 mol) was added, and the reaction mixture was stirred overnight at room temperature. The mixture was filtered and the solid product was washed with acetone (100 ml) and then thoroughly with ether. After drying, 199 g (0.81 mol, 81%) of the title compound were obtained, M.P. 145°-150° C.

Fuente