Reacción #167636

ord-52cf2503004c45928c3378e0e38b949a

Ecuación de reacción

Brc1cncc(N2CC3CC4CC2CN(C4)C3)c1
product
Brc1cncc(N2CC3CC4CC2CN(C4)C3)c1
4-(5-Bromopyridin-3-yl)-1,4-diazatricyclo[4.3.1.13,8]undecane
OB(O)c1ccc2[nH]ccc2c1
1H-indol-5-ylboronic acid
→
c1cc2cc(-c3cncc(N4CC5CC6CC4CN(C6)C5)c3)ccc2[nH]1
title compound
c1cc2cc(-c3cncc(N4CC5CC6CC4CN(C6)C5)c3)ccc2[nH]1
4-[5-(1H-indol-5-yl)pyridin-3-yl]-1,4-diazatricyclo[4.3.1.13,8]undecane

Reactantes

Brc1cncc(N2CC3CC4CC2CN(C4)C3)c1
product
Brc1cncc(N2CC3CC4CC2CN(C4)C3)c1
4-(5-Bromopyridin-3-yl)-1,4-diazatricyclo[4.3.1.13,8]undecane
OB(O)c1ccc2[nH]ccc2c1
1H-indol-5-ylboronic acid

Reactivos

Ninguno

Condiciones de reacción

Condiciones detalladas
See reaction.notes.procedure_details.

Procedimiento

The title compound was prepared from the product of Example 65A and 1H-indol-5-ylboronic acid according to General Method B: LC-MS Method D (ESI+) m/z 344.0 (M+H)+, retention time 1.30 minutes.

Fuente

DOI: 10.6084/m9.figshare.5104873.v1Patente: US08846661B2uspto-grants-2014_09