Reacción #167612

ord-85fe9c1efb744f2a91214497ae7499c3

Ecuación de reacción

Brc1cncc(N2CC3CC4CC2CN(C4)C3)c1
product
Brc1cncc(N2CC3CC4CC2CN(C4)C3)c1
4-(5-Bromopyridin-3-yl)-1,4-diazatricyclo[4.3.1.13,8]undecane
OB(O)c1ccc(C(F)(F)F)cc1
4-trifluoromethylphenylboronic acid
FC(F)(F)c1ccc(-c2cncc(N3CC4CC5CC3CN(C5)C4)c2)cc1
title compound
FC(F)(F)c1ccc(-c2cncc(N3CC4CC5CC3CN(C5)C4)c2)cc1
4-{5-[4-(trifluoromethyl)phenyl]pyridin-3-yl}-1,4-diazatricyclo[4.3.1.13,8]undecane

Condiciones de reacción

Condiciones detalladas
See reaction.notes.procedure_details.

Procedimiento

The title compound was prepared from the product of Example 65A and 4-trifluoromethylphenylboronic acid according to General Method B: LC-MS Method D (ESI+) m/z 374.0 (M+H)+, retention time 1.47 minutes.

Fuente

DOI: 10.6084/m9.figshare.5104873.v1Patente: US08846661B2uspto-grants-2014_09