Reacción #162967

ord-322dca9a27144c6eb27e52f55e69c7c5

Condiciones de reacción

Condiciones detalladas
See reaction.notes.procedure_details.

Tratamiento posterior

  1. 1
    Otrowas obtained in 95.2% yield

Procedimiento

The title compound was prepared from 3-{4-[3-(4-fluoro-phenyl)-ureido]-phenyl}-isoxazole-5-carboxylic acid ethyl ester using the procedure as set forth in Example 8 and was obtained in 95.2% yield. Mass (ES+): 342 (M++1); IR (KBr): 3307, 3004 (br), 2871 (br), 1711, 1640, 1601, 1546; 1H NMR (DMSO-d6) δ: 7.08 (t, 2H), 7.43 (m, 2H), 7.49 (d, 2H), 7.67 (s, 1H), 7.84 (d, 2H), 8.77 (s, 1H), 8.93 (s, 1H).

Fuente

DOI: 10.6084/m9.figshare.5104873.v1Patente: US08835428B2uspto-grants-2014_09