Reacción #162265

Ecuación de reacción

methacrylate ester

7-Tert-butoxycarbonyl-2-oxohexahydro-3,5-methano-2H-cyclopenta[b]furane-6-yl Methacrylate

→

intended product

Rendimiento 81.0%

6-Methacryloyloxy-2-oxohexahydro-3,5-methano-2H-cyclopenta[b]furane-7-carboxylic Acid

Rendimiento 81.0%

Disolventes

formic acid

Condiciones de reacción

Tratamiento posterior

1. 1
   Otroobtained in Synthesis Example 1-1-1
2. 2
   OtroAfter formic acid was removed by distillation under reduced pressure, recrystallization

Procedimiento

Dissolved into 810 g of formic acid was 202.2 g of the methacrylate ester (25) obtained in Synthesis Example 1-1-1; and then, the resulting mixture was stirred at 25° C. for 16 hours. After formic acid was removed by distillation under reduced pressure, recrystallization was made from ethyl acetate to give 135.1 g of the intended product (Yield 81%).

Fuente