Reacción #1619

ord-a3c93df638364213adea34d2adfb06d5

Condiciones de reacción

Condiciones detalladas
See reaction.notes.procedure_details.

Tratamiento posterior

  1. 1
    TemperaturaAfter cooling
  2. 2
    Otrothe solvent was evaporated
  3. 3
    Otrothe residue was dried

Procedimiento

A solution of (R)-3-(3,4-dimethoxyphenyl)-2-propylamine hydrochloride1 (500 mg, 2.15 mMol) in hydrogen bromide (48%, 5 ml) was stirred at 100° C. under an argon atmosphere for 20 hours. After cooling, the solvent was evaporated and the residue was dried giving the title compound.

Fuente

DOI: 10.6084/m9.figshare.5104873.v1Patente: US05726165uspto-grants-1998_03