Reacción #1608

Ecuación de reacción

6-(4-chlorophenyl)-pyridazinone

phosphorus pentasulfide

→

6-(4-chlorophenyl)-pyridazinthione

Rendimiento 187.1%

Disolventes

pyridine

Condiciones de reacción

Tratamiento posterior

1. 1
   Temperaturawas refluxed for 1 hour
2. 2
   Otroevaporated to dryness
3. 3
   Extracciónextracted with 200 ml of ether
4. 4
   ExtracciónThe ether extract
5. 5
   Lavadowas washed with water (3×100 ml), brine (100 ml)
6. 6
   Secadodried over magnesium sulfate
7. 7
   Otroevaporated

Procedimiento

A mixture of 3.0 g of 6-(4-chlorophenyl)-pyridazinone, 50 ml of dry pyridine and 3.2 g of phosphorus pentasulfide was refluxed for 1 hour, evaporated to dryness and extracted with 200 ml of ether. The ether extract was washed with water (3×100 ml), brine (100 ml), dried over magnesium sulfate and evaporated to yield 3.0 g of 6-(4-chlorophenyl)-pyridazinthione as a yellow solid.

Fuente