Reacción #1605811

Ecuación de reacción

2-Phenylaniline

acetic anhydride

→

2-phenyl-N-acetylaniline

Rendimiento 99.5%

Disolventes

acetic acid

Condiciones de reacción

Tratamiento posterior

1. 1
   ConcentraciónThe solution was concentrated under reduced pressure
2. 2
   workup.ADDITIONto the residue was added water (15 mL)
3. 3
   workup.STIRRINGthe mixture was stirred at room temperature for 3 hours
4. 4
   FiltraciónThe precipitate was collected by filtration
5. 5
   Lavadowashed with purified water
6. 6
   Otrodried under reduced pressure

Procedimiento

2-Phenylaniline (5 g, 29.55 mmol) was dissolved in acetic acid (30 mL), acetic anhydride (3.62 g, 35.45 mmol) was added thereto under ice bath, and the mixture was stirred under ice bath for 2 hours. The solution was concentrated under reduced pressure. to the residue was added water (15 mL), and the mixture was stirred at room temperature for 3 hours. The precipitate was collected by filtration, washed with purified water, and dried under reduced pressure to obtain 2-phenyl-N-acetylaniline (6.21 g).

Fuente