Reacción #1603304

Ecuación de reacción

2-hydroxy-4-methylpyridine

acetyl hypofluorite

→

2-acetoxy-4-methylpyridine

Condiciones de reacción

Procedimiento

As a process for the preparation of 2-hydroxy-4-methylpyridine, a process whereby [iv]-4-methylpyridine is reacted with acetyl hypofluorite at −10° C. to obtain a 2-acetoxy-4-methylpyridine, and thereafter the 2-acetoxy-4-methylpyridine is hydrolyzed to obtain 4-methyl-2-pyridone is reported [Journal of the American Chemical Society, 109, 3789-3790, (1987): Non-Patent Reference 2].

Fuente