Reacción #1597188

Ecuación de reacción

6-(6,7-dimethoxyquinazolin-4-yloxy)-1-naphthoic acid

4-(aminomethyl)-N-(2-aminophenyl)benzamide

→

title compound

Rendimiento 72.0%

N-(4-((2-aminophenyl)carbamoyl)benzyl)-6-(6,7-dimethoxyquinazolin-4-yloxy)-1-naphthamide

Rendimiento 72.0%

Condiciones de reacción

Procedimiento

The title compound (43.1 mg, 72% yield) was prepared as a brown solid from 6-(6,7-dimethoxyquinazolin-4-yloxy)-1-naphthoic acid (37.6 mg, 0.1 mmol) and 4-(aminomethyl)-N-(2-aminophenyl)benzamide (28.9 mg, 0.12 mmol) by an analogous procedure to that described in example 16. LC-MS (m/z) 600 (M+1).

Fuente