Reacción #1596997

Ecuación de reacción

5-aminosalicylic acid

4-(trifluoromethyl)benzyl chloride

→

5-(4-(trifluoromethyl)benzyl)aminosalicylic acid

Rendimiento 50.3%

Condiciones de reacción

Tratamiento posterior

1. 1
   Otroin Synthesis Example 1

Procedimiento

By following the similar procedure in Synthesis Example 1 by using 5-aminosalicylic acid (500 mg, 3.26 mmole) and 4-(trifluoromethyl)benzyl chloride (760 mg, 3.92 mmole), 510 mg (50% yield) of 5-(4-(trifluoromethyl)benzyl)aminosalicylic acid was obtained as a white solid.:mp>188° C. (decompose).

Fuente