Reacción #1596996

Ecuación de reacción

5-aminosalicylic acid

4-chlorobenzyl chloride

→

5-(4-chlorobenzyl)aminosalicylic acid

Rendimiento 53.0%

Condiciones de reacción

Tratamiento posterior

1. 1
   Otroin Synthesis Example 1

Procedimiento

By following the similar procedure in Synthesis Example 1 by using 5-aminosalicylic acid (500 mg, 3.26 mmole) and 4-chlorobenzyl chloride (630 mg, 3.91 mmole), 480 mg (53% yield) of 5-(4-chlorobenzyl)aminosalicylic acid was obtained as a white solid.:mp 227-228° C.

Fuente