Reacción #1596523

Ecuación de reacción

diphenyliodonium chloride

triethylammonium 2-pivaloyloxy-1,1-difluoroethanesulfonate

water

→

target compound

Rendimiento 96.6%

Diphenyliodonium 2-Pivaloyloxy-1,1-difluoroethanesulfonate

Rendimiento 96.6%

Disolventes

chloroform

Condiciones de reacción

Tratamiento posterior

1. 1
   Otroreacted at room temperature for 3 hours
2. 2
   OtroThe thus-obtained reaction solution
3. 3
   Otrowas separated into an organic layer
4. 4
   LavadoThe organic layer was washed five times with 15 mL of water
5. 5
   Concentraciónsubjected to concentration under reduced pressure

Procedimiento

In 10 mL of chloroform, 5 g of a solid of triethylammonium 2-pivaloyloxy-1,1-difluoroethanesulfonate (equivalent to 14.4 mmol) was dissolved by stirring. The resulting solution was admixed with 15 mL of water and 4.78 g (15.1 mmol) of diphenyliodonium chloride, and then, reacted at room temperature for 3 hours. The thus-obtained reaction solution was separated into an organic layer and an aqueous layer. The organic layer was washed five times with 15 mL of water and subjected to concentration under reduced pressure. With this, 7.32 g of the target compound was obtained as a white solid (purity: 90%, yield: 90%).

Fuente