Reacción #159175

Ecuación de reacción

1-(3a,6a-Dihydro-thieno[3,2-b]thiophen-2-yl)-ethanone

phenyltrimethylammonium tribromide

→

title compound

2-Bromo-1-(3a,6a-dihydro-thieno[3,2-b]thiophen-2-yl)-ethanone

Disolventes

THF

Condiciones de reacción

Tratamiento posterior

1. 1
   Filtraciónthe suspension was filtered over CELITE
2. 2
   workup.ADDITIONThe filtrate was diluted with diethyl ether
3. 3
   Lavadowashed with saturated aqueous NaHCO3 and brine
4. 4
   Secadothen dried over MgSO4
5. 5
   Filtraciónfiltered
6. 6
   Concentraciónconcentrated

Procedimiento

1-(3a,6a-Dihydro-thieno[3,2-b]thiophen-2-yl)-ethanone (453 mg, 2.48 mmol) was dissolved in THF (12 mL) and phenyltrimethylammonium tribromide (932 mg, 2.48 mmol) was added. After stirring for 1 h, the suspension was filtered over CELITE. The filtrate was diluted with diethyl ether, then washed with saturated aqueous NaHCO3 and brine then dried over MgSO4, filtered and concentrated to afford the title compound which was carried on without purification.

Fuente