Reacción #158394

Ecuación de reacción

ethyl 2-azido-7-[3-methoxy-4-(2-methyl-1,3-oxazol-5-yl)phenyl]hept-6-ynoate

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title compound

Rendimiento 95.7%

ethyl 3-[3-methoxy-4-(2-methyl-1,3-oxazol-5-yl)phenyl]-4,5,6,7-tetrahydro[1,2,3]triazolo[1,5-a]pyridine-7-carboxylate

Rendimiento 95.7%

Disolventes

chlorobenzene

Condiciones de reacción

Tratamiento posterior

1. 1
   OtroThe reaction mixture was purified by silica gel column chromatography (ethyl acetate/hexane)

Procedimiento

A mixture of ethyl 2-azido-7-[3-methoxy-4-(2-methyl-1,3-oxazol-5-yl)phenyl]hept-6-ynoate (1.40 g) in chlorobenzene (28 mL) was stirred at 110° C. for 4 hr. The reaction mixture was purified by silica gel column chromatography (ethyl acetate/hexane) to give the title compound (1.34 g).

Fuente