Reacción #1573587

ord-78915987281748619bd18382a53ec2c7

Ecuación de reacción

N[C@H](C(=O)O)C1CCOCC1
(S)-2-amino-2-(tetrahydro-2H-pyran-4-yl)acetic acid
COC(=O)N[C@H](C(=O)O)C(C)C
N-methoxycarbonyl-L-Valine
→
COC(=O)NC(C(=O)O)C1CCOCC1
2-(methoxycarbonylamino)-2-(tetrahydro-2H-pyran-4-yl)acetic acid

Reactantes

N[C@H](C(=O)O)C1CCOCC1
(S)-2-amino-2-(tetrahydro-2H-pyran-4-yl)acetic acid
COC(=O)N[C@H](C(=O)O)C(C)C
N-methoxycarbonyl-L-Valine

Reactivos

Ninguno

Condiciones de reacción

Condiciones detalladas
See reaction.notes.procedure_details.

Procedimiento

2-(methoxycarbonylamino)-2-(tetrahydro-2H-pyran-4-yl)acetic acid was synthesized similar to N-methoxycarbonyl-L-Valine, using (S)-2-amino-2-(tetrahydro-2H-pyran-4-yl)acetic acid instead of L-Valine.

Fuente

DOI: 10.6084/m9.figshare.5104873.v1Patente: US09427428B2uspto-grants-2016_08