Reacción #157227

ord-aa2bcf7a3f0d4325bdbafbfcb4f99bbb

Ecuación de reacción

COc1cc(C(=O)c2csc(-c3ccccc3)n2)cc(OC)c1OC
compound 1h
COc1cc(C(=O)c2csc(-c3ccccc3)n2)cc(OC)c1OC
(2-Phenyl-thiazol-4-yl)-(3,4,5-trimethoxy-phenyl)-methanone
N#Cc1ccc(C#N)cc1
terephthalonitrile
N[C@@H](CS)C(=O)O
cysteine
COc1cc(C(=O)c2csc(-c3ccc(CC#N)cc3)n2)cc(OC)c1OC
2-(4-(4-(3,4,5-Trimethoxybenzoyl)thiazol-2-yl)phenyl)acetonitrile

Condiciones de reacción

Condiciones detalladas
See reaction.notes.procedure_details.

Procedimiento

2-(4-(4-(3,4,5-Trimethoxybenzoyl)thiazol-2-yl)phenyl)acetonitrile (2n) was prepared using the same method as used of compound 1h from terephthalonitrile and cysteine. 1H NMR (500 MHz, CDCl3) δ 8.30 (s, 1H), 8.04 (d, 2H), 7.76 (s, 2H), 7.46 (d, 2H), 3.97 (s, 3H), 3.95 (s, 6H), 3.83 (s, 2H).

Fuente

DOI: 10.6084/m9.figshare.5104873.v1Patente: US08822513B2uspto-grants-2014_09