Reacción #157017

Ecuación de reacción

4-chloro-3-nitropyridine

N1,N1,N2-trimethyl ethane-1,2-diamine

DIEA

→

N1,N1,N2-trimethyl-N2-(3-nitropyridin-4-yl)ethane-1,2-diamine

Disolventes

EtOH

Condiciones de reacción

Procedimiento

The method of Example 1 was followed using 4-chloro-3-nitropyridine (1.0 eq), N1,N1,N2-trimethyl ethane-1,2-diamine (2.0 eq), and DIEA (2.0 eq) in EtOH yielding N1,N1,N2-trimethyl-N2-(3-nitropyridin-4-yl)ethane-1,2-diamine which was concentrated and taken on as is. LCMS (m/z): 225.1 (MH+); LC Rt=0.574 min.

Fuente