Reacción #155368

Ecuación de reacción

1b

3-[(3-Amino-4-methylamino-benzoyl)-phenyl-amino]-propionic acid methyl ester

N-(4-cyano-phenyl)-glycine

CDI

→

3-({3-[2-(4-Cyano-phenylamino)-acetylamino]-4-methylamino-benzoyl}-phenyl-amino)-propionic acid methyl ester

Disolventes

THF

Condiciones de reacción

Tratamiento posterior

1. 1
   OtroAfter completion of the reaction the mixture
2. 2
   Otrowas evaporated to dryness
3. 3
   Otrothe crude product was used without further purification

Procedimiento

The product of 1b (23.2 mmol) and N-(4-cyano-phenyl)-glycine (23.2 mmol) were coupled with CDI (23.2 mmol) in dry THF at room temperature. After completion of the reaction the mixture was evaporated to dryness and the crude product was used without further purification.

Fuente