Reacción #1552054

Ecuación de reacción

methyl-4-bromobenzoate

hydrazine monohydrate

→

white solid

Rendimiento 67.0%

4-bromobenzohydrazide

Rendimiento 67.0%

Disolventes

ethanol

Condiciones de reacción

Tratamiento posterior

1. 1
   Temperaturathe mixture was heated
2. 2
   workup.STIRRINGstirred at 78° C. for 5 hours
3. 3
   OtroA solid obtained
4. 4
   Lavadowashed with water
5. 5
   Filtracióncollected by suction filtration

Procedimiento

First, 3.0 g (13.9 mmol) of methyl-4-bromobenzoate was put in a 100-mL three-neck flask, 10 mL of ethanol was added therein, and the mixture was stirred. Thereafter, 4.0 mL of hydrazine monohydrate was added therein, and the mixture was heated and stirred at 78° C. for 5 hours. A solid obtained washed with water and collected by suction filtration; thus, 2.0 g of a white solid of objective 4-bromobenzohydrazide was obtained (yield: 67%).

Fuente