Reacción #1552050

Ecuación de reacción

1,8-octanediamine

triethylamine

furoyl chloride

→

N,N′-(octane-1,8-diyl)bis(furan-2-carboxamide)

Condiciones de reacción

Tratamiento posterior

1. 1
   OtroThe resulting compound was purified by column chromatography (98:2 DCM:EtOAc)
2. 2
   Otrothe product obtained as a white solid (21.5 g/92%)

Procedimiento

The general procedure was carried out using 1,8-octanediamine (10.0 g, 69.3 mmol), triethylamine (14.2 g, 141 mmol), DMAP (0.17 g, 1.35 mmol) and furoyl chloride (19.0 g, 146 mmol). The resulting compound was purified by column chromatography (98:2 DCM:EtOAc), and the product obtained as a white solid (21.5 g/92%).

Fuente