Reacción #1549595

Ecuación de reacción

2-[2-(4-chlorophenyl)-5-(3-thienyl)-4-oxazolyl]acetic acid

2-chloro-1-methyl-pyridinium iodide

n-butanol

→

n-butyl 2-[2-(4-chlorophenyl)-5-(3-thienyl)-4-oxazolyl]acetate

Rendimiento 69.6%

Disolventes

triethylamine

Condiciones de reacción

Procedimiento

0.55 g of 2-[2-(4-chlorophenyl)-5-(3-thienyl)-4-oxazolyl]acetic acid, 0.44 g of 2-chloro-1-methyl-pyridinium iodide, 0.13 ml of n-butanol and 0.2 g of triethylamine are treated in the same manner as described in Example 20. 0.45 g of n-butyl 2-[2-(4-chlorophenyl)-5-(3-thienyl)-4-oxazolyl]acetate is thereby obtained.

Fuente