Reacción #1549592

Ecuación de reacción

2-[2-(4-fluorophenyl)-5-(3-thienyl)-4-oxazolyl]acetic acid

potassium hydroxide

oxalyl chloride

n-butanol

→

n-butyl 2-[2-(4-fluorophenyl)-5-(3-thienyl)-4-oxazolyl]acetate

Rendimiento 42.2%

Condiciones de reacción

Procedimiento

2 g of 2-[2-(4-fluorophenyl)-5-(3-thienyl)-4-oxazolyl]acetic acid, 0.5 g of potassium hydroxide, 4.2 g of oxalyl chloride and 20 ml of n-butanol are treated in the same manner as described in Example 17. One g of n-butyl 2-[2-(4-fluorophenyl)-5-(3-thienyl)-4-oxazolyl]acetate is thereby obtained. Yield: 42.2%

Fuente