Reacción #1549581

Ecuación de reacción

methyl 3-(4-chlorobenzoylamino)-3-(3-thienylcarbonyl)propionate

phosphorus oxychloride

→

methyl 2-[2-(4-chlorophenyl)-5-(3-thienyl)-4-oxazolyl]acetate

Rendimiento 89.2%

Disolventes

dimethylformamide

Condiciones de reacción

Procedimiento

13 g of methyl 3-(4-chlorobenzoylamino)-3-(3-thienylcarbonyl)propionate, 50 ml of dimethylformamide and 9.6 g of phosphorus oxychloride are treated in the same manner as described in Example 1. 11 g of methyl 2-[2-(4-chlorophenyl)-5-(3-thienyl)-4-oxazolyl]acetate are thereby obtained.

Fuente