Reacción #1519130

ord-00b1c3a720e54615b517efd6b51572bc

Ecuación de reacción

c1ccc(C2CCNC2)cc1
3-phenyl-pyrrolidine
CCCCC(C(=O)O)C1OC(C)(C)OC1=O
2-(2,2-dimethyl-4-oxo-1,3-dioxolan-5-yl)hexanoic acid
→
CCCC[C@@H](C(=O)N1CCC(c2ccccc2)C1)[C@H](O)C(=O)O
title compound
CCCC[C@@H](C(=O)N1CCC(c2ccccc2)C1)[C@H](O)C(=O)O
(S)-hydroxy-3 (R)-[3 (R/S)-phenyl-pyrrolidine-1-carbonyl)-heptanoic acid

Reactantes

c1ccc(C2CCNC2)cc1
3-phenyl-pyrrolidine
CCCCC(C(=O)O)C1OC(C)(C)OC1=O
2-(2,2-dimethyl-4-oxo-1,3-dioxolan-5-yl)hexanoic acid

Reactivos

Ninguno

Condiciones de reacción

Condiciones detalladas
See reaction.notes.procedure_details.

Procedimiento

The title compound is prepared from 2-(2,2-dimethyl-4-oxo-1,3-dioxolan-5-yl)hexanoic acid B-5 and commercially available 3-phenyl-pyrrolidine A-5 according to General Procedure B.

Fuente

DOI: 10.6084/m9.figshare.5104873.v1Patente: US07612059B2uspto-grants-2009_11