Reacción #1519127

ord-d0d50ff850ca4131a0261cebd6a81476

Ecuación de reacción

c1cc(C2CCCN2)ccn1
4-pyrrolidin-2-yl-pyridine
CCCCC(C(=O)O)C1OC(C)(C)OC1=O
2-(2,2-dimethyl-4-oxo-1,3-dioxolan-5-yl)hexanoic acid
→
CCCC[C@@H](C(=O)N1CCCC1c1ccncc1)[C@H](O)C(=O)O
title compound
CCCC[C@@H](C(=O)N1CCCC1c1ccncc1)[C@H](O)C(=O)O
(S)-hydroxy-3 (R)-[2-pyridin-4-yl-pyrrolidine-1-carbonyl)-heptanoic acid

Reactantes

c1cc(C2CCCN2)ccn1
4-pyrrolidin-2-yl-pyridine
CCCCC(C(=O)O)C1OC(C)(C)OC1=O
2-(2,2-dimethyl-4-oxo-1,3-dioxolan-5-yl)hexanoic acid

Reactivos

Ninguno

Condiciones de reacción

Condiciones detalladas
See reaction.notes.procedure_details.

Procedimiento

The title compound is prepared from 2-(2,2-dimethyl-4-oxo-1,3-dioxolan-5-yl)hexanoic acid B-5 and commercially available 4-pyrrolidin-2-yl-pyridine A-5 according to General Procedure B.

Fuente

DOI: 10.6084/m9.figshare.5104873.v1Patente: US07612059B2uspto-grants-2009_11