Reacción #1519094

Ecuación de reacción

4-Benzyloxybenzyl chloride

triphenyl phosphine

ether

→

4-benzyloxybenzyltriphenyl phosphonium chloride

Disolventes

toluene

Condiciones de reacción

Tratamiento posterior

1. 1
   FiltraciónThe precipitated phosphonium salt was collected by filtration
2. 2
   Lavadorinsed with ether and air
3. 3
   Otrodried

Procedimiento

4-Benzyloxybenzyl chloride (1 g, 0.0043 moles) and triphenyl phosphine (1.127 g, 1 equivalent) in anhydrous toluene (20 mL) were refluxed under nitrogen for ˜8-10 hours. A white precipitate appeared in the reaction mixture. The reaction mixture was then cooled to room temperature and ether (100 mL) was added. The precipitated phosphonium salt was collected by filtration, rinsed with ether and air dried. Yield=0.55 g (25%). MALDI-TOF MS 459.51 obs. (459.54 calc.).

Fuente