Reacción #1478592

Ecuación de reacción

4-carboxybenzaldehyde

trimethylsilyl chloride

→

4-methoxycarbonylbenzaldehyde

Disolventes

MeOH

Condiciones de reacción

Tratamiento posterior

1. 1
   OtroAfter evaporation

Procedimiento

The 4-carboxybenzaldehyde is of commercial origin. It is dissolved (3 g; 20 mmol) in a trimethylsilyl chloride solution (10 g; 92 mmol) in 100 ml of MeOH. The mixture is kept stirred for 40 h at room temperature. After evaporation, a white solid corresponding to 4-methoxycarbonylbenzaldehyde 24 is isolated, characterized by NMR and used as it is for the next reaction.

Fuente