Reacción #1478584

Ecuación de reacción

Pantothenic acid

DL-pantolactone

formaldehyde

cyanide

→

D-pantothenic acid

Condiciones de reacción

Tratamiento posterior

1. 1
   Otroin further process steps, the racemic mixture is separated
2. 2
   OtroD-pantolactone is subjected to a condensation reaction with β-alanine

Procedimiento

Pantothenic acid can be prepared by chemical synthesis, or biotechnologically by fermentation of suitable microorganisms in suitable nutrient solutions. In the chemical synthesis, DL-pantolactone is an important precursor. It is prepared in a multi-stage process from formaldehyde, isobutylaldehyde and cyanide, and in further process steps, the racemic mixture is separated, D-pantolactone is subjected to a condensation reaction with β-alanine, and D-pantothenic acid is obtained in this way.

Fuente