Reacción #1470425

Ecuación de reacción

1-oxyl-2,2,6,6-tetramethyl-4-glycidyloxypiperidine

diethanolamine

→

title compound

Rendimiento 29.9%

1-Oxyl-2,2,6,6-tetramethyl-4-{2-hydroxy-3-[di(2-hydroxyethyl)amino]propoxy}piperidine

Rendimiento 29.9%

Disolventes

water

Condiciones de reacción

Tratamiento posterior

1. 1
   ExtracciónThe solution is then extracted with methylene chloride
2. 2
   ExtracciónThe methylene chloride extract
3. 3
   Secadois dried over anhydrous magnesium sulfate
4. 4
   Filtraciónfilter
5. 5
   Concentraciónconcentrated
6. 6
   OtroThe crude reaction product
7. 7
   Otrois purified by column chromatography

Procedimiento

A solution of 2.28 g (0.01 mol) of 1-oxyl-2,2,6,6-tetramethyl-4-glycidyloxypiperidine and 1.05 g (0.01 mol) of diethanolamine in 25 mL of water is stirred at ambient temperature for 16 hours. The solution is then extracted with methylene chloride. The methylene chloride extract is dried over anhydrous magnesium sulfate, filter and concentrated. The crude reaction product is purified by column chromatography to afford 1.0 g of the title compound as a red oil.

Fuente