Reacción #1463490

Ecuación de reacción

bromine

bromine

water

sodium sulfite

bromine

EPAQ

1-(1-ethylpropylamino)anthraquinone

→

1-(1-ethylpropylamino)-4-bromoanthraquinone

Disolventes

acetic acid

acetic acid

Condiciones de reacción

Tratamiento posterior

1. 1
   workup.ADDITIONwas added
2. 2
   OtroThe aqueous solution was decanted off
3. 3
   workup.DISSOLUTIONThe solid was dissolved in methylene chloride
4. 4
   Concentraciónconcentrated
5. 5
   workup.ADDITIONslowly added to cold methanol, whereupon a solid
6. 6
   Otroprecipitated

Procedimiento

EPAQ (20.02 g) was dissolved in hot acetic acid. In a separate flask, bromine (12.03 g) was dissolved in acetic acid (ca. 10 mL). The bromine solution was slowly added to the dye solution. The reaction was allowed to proceed for 1/2 hour, with occasional shaking. The reaction mixture was poured into water (600 mL), and aqueous sodium sulfite was added to discharge the bromine. The aqueous solution was decanted off. The solid was dissolved in methylene chloride, then concentrated, and slowly added to cold methanol, whereupon a solid precipitated.

Fuente