Reacción #1463483

Ecuación de reacción

cyclohexane

4-(4-propylphenyl)phenylcyclohexane

toluene

formic acid

→

3-(4-(4-(4-propylphenyl)phenyl)cyclohexyl)propanal

Condiciones de reacción

Tratamiento posterior

1. 1
   Temperaturaheating the mixture
2. 2
   Temperaturaunder reflux for 5 hours
3. 3
   Lavadowashing the reaction mixture with water after completion of the stirring
4. 4
   Secadodrying over anhydrous magnesium sulfate
5. 5
   Concentraciónconcentrating under reduced pressure
6. 6
   Otroisolating the resulting yellow oil

Procedimiento

This cyclohexane derivative (11.8 g, 30 mmols) was dissolved in toluene (100 ml), followed by adding formic acid (5 ml), heating the mixture under reflux for 5 hours, washing the reaction mixture with water after completion of the stirring, drying over anhydrous magnesium sulfate, concentrating under reduced pressure and isolating the resulting yellow oil to obtain 3-(4-(4-(4-propylphenyl)phenyl)cyclohexyl)propanal. This product is used in the subsequent reaction with any purification.

Fuente