Reacción #1447111

Ecuación de reacción

Et3N

1-naphthol

phosphorus oxychloride

→

title compound

1-Naphthyl dichlorophosphate

Disolventes

Et2O

Condiciones de reacción

Tratamiento posterior

1. 1
   workup.WAITthe resulting solution was left
2. 2
   Temperaturato warm to RT overnight
3. 3
   FiltraciónThe white slurry was filtered under an inert atmosphere
4. 4
   Otroall volatiles were removed

Procedimiento

To 1-naphthol in Et2O (0.23 M) was added phosphorus oxychloride (1.0 eq.) and the solution was cooled to −78° C. Neat Et3N (1.0 eq) was added and the resulting solution was left to warm to RT overnight. The white slurry was filtered under an inert atmosphere and all volatiles were removed to yield the title compound as a colorless liquid that was used without further purification in the next step. 31P NMR (400 MHz, CDCl3): δ 3.93 ppm.

Fuente