Reacción #1442484

Ecuación de reacción

Boric acid

glycerol

salicylamide

→

salicylamide glycerol borate

Rendimiento 88.2%

Disolventes

toluene

Condiciones de reacción

Tratamiento posterior

1. 1
   OtroSalicylamide/glycerol borate was prepared
2. 2
   Otrothe byproduct water (˜9 grams) was continuously removed from the reaction by azeotropic distillation
3. 3
   OtroThe final solution was evaporated
4. 4
   Otroto remove toluene under vacuum

Procedimiento

Salicylamide/glycerol borate was prepared as follows. Boric acid (10.3 grams), glycerol (15.3 grams), and salicylamide (22.9 grams) were added to a 250 milliliter flask. One hundred fifty milliliters of toluene was then added. The reaction was allowed to proceed overnight at 110° C., and the byproduct water (˜9 grams) was continuously removed from the reaction by azeotropic distillation. The final solution was evaporated to remove toluene under vacuum, and a yellowish resinous product (˜40 grams) of salicylamide/glycerol borate was obtained.

Fuente