Reacción #1400

Ecuación de reacción

4,4'-difluorodiphenylmethane

sulfuric acid

→

4,4'-difluorobenzophenone

Rendimiento 54.0%

Disolventes

water

Condiciones de reacción

Tratamiento posterior

1. 1
   workup.ADDITIONare first mixed
2. 2
   workup.ADDITIONis added

Procedimiento

The procedure of Example 2 is used except that the 4,4'-difluorodiphenylmethane, water, and sulfuric acid are first mixed, then heated before the MnO2 is added. The yield is 54% 4,4'-difluorobenzophenone that is 95% pure.

Fuente