Reacción #1368947

ord-9a6d2d9b366444dca939fb39882a64d9

Ecuación de reacción

CCOC(=O)c1c(N)sc2cc(OC)ccc12
ethyl 2-amino-6-methoxybenzo[b]thiophene-3-carboxylate
O=[N+]([O-])c1ccc(F)cc1F
2,4-difluoronitrobenzene
→
CCOC(=O)c1c(Nc2cc(F)ccc2[N+](=O)[O-])sc2cc(OC)ccc12
ethyl 2-(5-fluoro-2-nitroanilino)-6-methoxybenzo[b]thiophene-3-carboxylate

Reactantes

CCOC(=O)c1c(N)sc2cc(OC)ccc12
ethyl 2-amino-6-methoxybenzo[b]thiophene-3-carboxylate
O=[N+]([O-])c1ccc(F)cc1F
2,4-difluoronitrobenzene

Reactivos

Ninguno

Disolventes

CS(C)=O
dimethyl sulfoxide

Condiciones de reacción

Condiciones detalladas
See reaction.notes.procedure_details.

Tratamiento posterior

  1. 1
    OtroMaterial Synthesis Example 4

Procedimiento

In the same manner as in Starting Material Synthesis Example 4 and using ethyl 2-amino-6-methoxybenzo[b]thiophene-3-carboxylate, 2,4-difluoronitrobenzene and dimethyl sulfoxide, ethyl 2-(5-fluoro-2-nitroanilino)-6-methoxybenzo[b]thiophene-3-carboxylate is obtained.

Fuente

DOI: 10.6084/m9.figshare.5104873.v1Patente: US06455521B1uspto-grants-2002_09