Reacción #1365704

Ecuación de reacción

sodium bicarbonate

sorbitol

→

Sodium Bicarbonate Sorbitol

Disolventes

water

Condiciones de reacción

Tratamiento posterior

1. 1
   workup.ADDITIONwere added to the mixture
2. 2
   OtroThe resulting precipitate was isolated by vacuum filtration
3. 3
   FiltraciónRoughly half the batch filtered rather well
4. 4
   Otrodried
5. 5
   Otrooven dried at 100° C. overnight
6. 6
   workup.ADDITIONA 5% (w/w) aqueous suspension of the material
7. 7
   Otrothen was prepared
8. 8
   workup.STIRRINGstirred for about 30 minutes
9. 9
   Temperaturawith gentle heating in order

Procedimiento

147 g (1.75 moles) of sodium bicarbonate, 540 g of water, and 390 g of a 70% sorbitol solution (i.e. 273 g of 100% sorbitol and 170 g of water) were mixed. 306 g (1.5 moles) of aluminum iso-propoxide, heated to 100° C., then were added to the mixture and stirred for 2 hours. The resulting precipitate was isolated by vacuum filtration. Roughly half the batch filtered rather well. The filtered liquid and unfiltered solid were recombined to prevent loss of sorbitol, air dried, and then oven dried at 100° C. overnight. A 5% (w/w) aqueous suspension of the material then was prepared, and stirred for about 30 minutes with gentle heating in order to ensure complete dispersion. The results are summarized in Table 1, and are as follows: ANC, 0.677; Appearance, translucent; Stability, excellent; Grittiness, none; Evaluation, acceptable.

Fuente