Reacción #1359633

Ecuación de reacción

2-(2-aminophenyl) indole

3,4-dihydroxyphenylacetic acid

→

2-(3,4-Dihydroxy-phenyl)-N-[2-(1H-indol-2-yl)-phenyl]-acetamide

Rendimiento 17.0%

Condiciones de reacción

Tratamiento posterior

1. 1
   OtroThe product was chromatographed on silica
2. 2
   Otro8, 2 Hz (1H), 6.66 d, 8 Hz (1H), 6.78 d, 2 Hz (1H), 7.03 t, 8 Hz (1H), 7.11 t, 8 Hz (1H), 7.25 t, 8 Hz (1H), 7.31–7.35 m (2H), 7.51 d, 7 Hz (1H), 7.55 dd, 8.1 Hz (1H), 7.99 d, 8 Hz (1H)

Procedimiento

Prepared from 2-(2-aminophenyl) indole and 3,4-dihydroxyphenylacetic acid in 17% yield. The product was chromatographed on silica. 100% Purity by LC/MS (230 DAD), Mass-spec [M+H+]=359, 1H NMR (MeOH-d4): 3.56 s (2H), 6.10 s (1H), 6.59 dd, 8, 2 Hz (1H), 6.66 d, 8 Hz (1H), 6.78 d, 2 Hz (1H), 7.03 t, 8 Hz (1H), 7.11 t, 8 Hz (1H), 7.25 t, 8 Hz (1H), 7.31–7.35 m (2H), 7.51 d, 7 Hz (1H), 7.55 dd, 8.1 Hz (1H), 7.99 d, 8 Hz (1H).

Fuente