Reacción #1350586

Ecuación de reacción

methyl 4-methylbenzothiazole-5-carboxylate

phosphoric acid

→

4-Methylbenzothiazole-5-carboxylic Acid

Disolventes

potassium hydroxide

Condiciones de reacción

Tratamiento posterior

1. 1
   Temperaturaheated
2. 2
   Temperaturaat reflux for 2.5 h
3. 3
   TemperaturaAfter cooling
4. 4
   FiltraciónThe product was filtered off
5. 5
   Otrosubsequently dried

Procedimiento

16.6 g of methyl 4-methylbenzothiazole-5-carboxylate (0.08 mol) were dissolved in 280 ml of 5% strength aqueous potassium hydroxide solution and heated at reflux for 2.5 h. After cooling, the mixture was acidified using phosphoric acid. The product was filtered off and subsequently dried.

Fuente