Reacción #1340564

Ecuación de reacción

acetyltriphenylene

NaOH

EtOH

I2

I2

→

2-triphenylenecarboxylic acid

acetyltriphenylene

Disolventes

pyridine

water

Condiciones de reacción

Tratamiento posterior

1. 1
   Otroat room temperature
2. 2
   Temperaturaat reflux for 45 min
3. 3
   TemperaturaAfter reflux for a further hour
4. 4
   Temperaturathe reaction mixture is heated
5. 5
   Temperaturato reflux for 2 h

Procedimiento

The reaction product obtained in step a) is admixed with 2.2 equivalents of I2 (based on the crude yield of acetyltriphenylene) in pyridine solvent at room temperature. Thereafter, the mixture is kept at reflux for 45 min, and then a further portion of I2 (1.0 equivalent) is added. After reflux for a further hour, NaOH, EtOH and water are added and the reaction mixture is heated to reflux for 2 h. 2-triphenylenecarboxylic acid is obtained in 76% yield (based on crude yield of acetyltriphenylene, or 74% based on triphenylene).

Fuente