Reacción #1253203

Ecuación de reacción

chlorine

3,4-dimethyl-2-pyrazolin-5-one

→

3,4-dimethyl-4-chloro-2-pyrazolin-5-one

Disolventes

1,2-dichloroethane

Condiciones de reacción

Tratamiento posterior

1. 1
   OtroAfter the reaction
2. 2
   Temperaturathe reaction mixture was cooled
3. 3
   Filtraciónfiltered
4. 4
   workup.DISTILLATIONThe solvent was then distilled off
5. 5
   OtroThe residue in the form of an oil was recrystallized from a 1:1 mixture of benzene and petroleum ether

Procedimiento

A chlorine gas was introduced into a solution of 3,4-dimethyl-2-pyrazolin-5-one in 1,2-dichloroethane, followed by gradual refluxing. After the reaction, the reaction mixture was cooled and filtered. The solvent was then distilled off. The residue in the form of an oil was recrystallized from a 1:1 mixture of benzene and petroleum ether, whereby 3,4-dimethyl-4-chloro-2-pyrazolin-5-one was obtained.

Fuente