Reacción #11965

Ecuación de reacción

compound

(S)-2-(4-(N-Boc-aminomethyl)benzoylamino)-4-(N-Boc-amino)butyric acid

hydrochloric acid dioxane

→

title compound

Rendimiento 189.4%

(S)-2-(4-aminomethylbenzoylamino)-4-aminobutyric acid

Rendimiento 189.4%

Disolventes

methanol

Condiciones de reacción

Tratamiento posterior

1. 1
   OtroAfter the reaction
2. 2
   Otrothe solvent was removed by distillation
3. 3
   Otrothe residue was dried

Procedimiento

The compound obtained in Example 60-2 (49.7 mg) was dissolved in methanol (0.5 ml) and 4 mol/l hydrochloric acid/dioxane solution (0.5 ml) was added. The mixture was stirred for 1.5 hours at room temperature. After the reaction, the solvent was removed by distillation and the residue was dried using a vacuum pump to obtain the title compound (52.4 mg) as a white solid.

Fuente