Reacción #1181651

Ecuación de reacción

[(R)-2-(2,5-Difluoro-phenyl)-1-(methoxy-methyl-carbamoyl)-ethyl]-carbamic acid tert-butyl ester

N-(2-Methylpyridin-3-yl)acetamide

→

title compound

[(R)-3-(3-Acetylaminopyridin-2-yl)-1-(2,5-difluorobenzyl)-2-oxopropyl]carbamic acid tert-butyl ester

Condiciones de reacción

Procedimiento

Using general procedure 2 with [(R)-2-(2,5-Difluoro-phenyl)-1-(methoxy-methyl-carbamoyl)-ethyl]-carbamic acid tert-butyl ester (4.85 mmol; 1.67 g) and N-(2-Methylpyridin-3-yl)acetamide (12.12 mmol; 1.82 g) gives the title compound.

Fuente