Reacción #1178486

Ecuación de reacción

methyl N-benzyloxycarbonyl-2,5-dideoxy-3-O-ethyl-2,5-imino-D-lyxofuranoside

trifluoroacetic acid

→

title compound

Rendimiento 77.0%

N-benzyloxycarbonyl-2,5-dideoxy-3-O-ethyl-2,5-imino-D-lyxose

Rendimiento 77.0%

Condiciones de reacción

Tratamiento posterior

1. 1
   ConcentraciónThe reaction liquor was concentrated under reduced pressure
2. 2
   Extracciónthe obtained residue was extracted with methylene chloride
3. 3
   LavadoThe extract was washed with saturated brine
4. 4
   Secadodried over anhydrous sodium sulfate
5. 5
   ConcentraciónThe solvent was concentrated under reduced pressure
6. 6
   Otrothe obtained residue was purified by thin layer chromatography (ethyl acetate

Procedimiento

To an aqueous solution (1 mL) of methyl N-benzyloxycarbonyl-2,5-dideoxy-3-O-ethyl-2,5-imino-D-lyxofuranoside, trifluoroacetic acid (1 mL) was added, and the mixture was stirred for three hours. The reaction liquor was concentrated under reduced pressure, and the obtained residue was extracted with methylene chloride. The extract was washed with saturated brine, and dried over anhydrous sodium sulfate. The solvent was concentrated under reduced pressure, and the obtained residue was purified by thin layer chromatography (ethyl acetate:n-hexane=1:1, v/v), to obtain the title compound (92 mg, 77%) as an oily matter.

Fuente