Reacción #1178393

Ecuación de reacción

methacrylic acid

chloromethyl(2-indanyl)ether

toluene

→

(indane-2-yloxy)methyl methacrylate

Rendimiento 90.0%

Disolventes

triethylamine

Condiciones de reacción

Tratamiento posterior

1. 1
   Temperaturacooling with agitation
2. 2
   OtroAfter a usual aqueous work-up, the solvent was removed by distillation
3. 3
   Otroto obtain a crude product
4. 4
   OtroIt was purified by a column chromatography

Procedimiento

Into a mixture of 103 g of methacrylic acid, 183 g of chloromethyl(2-indanyl)ether, and 1500 g of toluene was added 111 g of triethylamine under ice-cooling with agitation, and then the reaction mixture was agitated at room temperature for 16 hours. After a usual aqueous work-up, the solvent was removed by distillation to obtain a crude product. It was purified by a column chromatography to obtain 209 g of an objective product, (indane-2-yloxy)methyl methacrylate (yield 90%).

Fuente