Reacción #1174484

Ecuación de reacción

1,8-dichloroanthraquinone

benzylsulfonamide

potassium carbonate

chlorobenzene

→

1,8-bis(benzylsulfonylamino)anthraquinone

Disolventes

methanol

Condiciones de reacción

Tratamiento posterior

1. 1
   OtroA 100ml round bottom flask, equipped with a magnetic stirrer
2. 2
   Temperaturacooling condenser
3. 3
   TemperaturaThis mixture was refluxed for 2.0 hours
4. 4
   workup.ADDITIONwas added
5. 5
   Otroprecipitation
6. 6
   OtroThe solid was collected
7. 7
   Extracciónextracted with dichloromethane
8. 8
   workup.ADDITIONtreated with charcoal
9. 9
   Otrorecrystallized from a mixture of methanol and dichloromethane
10. 10
    Otroto afford a yellow product

Procedimiento

A 100ml round bottom flask, equipped with a magnetic stirrer and cooling condenser, was charged with 1,8-dichloroanthraquinone (1.0g), benzylsulfonamide (4.0g), copper acetate monohydrate (1.0g), potassium carbonate (1.4g) and chlorobenzene (20ml). This mixture was refluxed for 2.0 hours and cooled, whereupon methanol (100ml) was added to induce precipitation. The solid was collected, extracted with dichloromethane, treated with charcoal, and recrystallized from a mixture of methanol and dichloromethane to afford a yellow product.

Fuente